I would say tuberculosis, the bacteria has managed to infect 1 in 4 people in the world! It’s also one of the oldest infectious diseases to affect humans. The bacteria is incredibly good at infecting humans, it hides inside white blood cells and can stay there for decades!
Some strains of flu (influenza virus) are also very infectious.
TB is really infectious I agree. Also, many of the respiratory viruses (like colds and flu) are super-infectious because they are spread by droplets, which means they are spread when you sneeze, cough, and even talk!
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