SWEET question. How do white blood cells actually know where to go?
Some white cells are continually patrolling the body looking for signs of infection. If they discover anything, they’ll release a signal which attracts loads of other white blood cells to come and help.
It depends on the type of white blood cell, but as Max said the general idea is that the immune cells in the organ that has a problem (an infection, a tumor…) call for help, either by sending signals into the blood, or by sending some cells (for example dendritic cells) into the lymph nodes, where you have a reservoir of T cells, to fetch the right type of T cell to attack the problem.
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